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KMID : 0828520120160030158
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Journal of the Korean Geriatrics Society
2012 Volume.16 No. 3 p.158 ~ p.161
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A Case of Systemic Inflammatory Response Syndrome Secondary to an Acute Polyarticular Gout
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Cheon Ji-Hyun
Kim Ji-Ung
Kim Sun-Kwang
Ko Sung-Hyun
Jo Jun-Ho
Park Kun-Woo
Lee Jin-Suk
Park Hyoung-Yoel
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Abstract
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Gout occurs as a response to monosodium urate crystal (MSU) that is present in joints, bones and soft tissue. The classic symptoms of gouty arthritis are recurrent attacks of acute, markedly painful monoarticular or oligoarticular inflammation, but polyarthritis and chronic arthritis can occur. Differential diagnosis from infectious arthritis is important. A definitive diagnosis requires the direct identification of urate crystals in the joint and the exclusion of infection. We report the case of systemic inflammatory response syndrome (SIRS) developed from acute polyarticular gout. SIRS is characterized by loss of local control of inflammation or an overly activated response resulting in an exaggerated systemic response. The SIRS was presumably due to systemic effects of a localized inflammatory response to urate crystals.
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KEYWORD
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Gout, Systemic inflammatory response syndrome, Sepsis
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